I'm not certain there is an optimum ratio is for any given population size, especially if many of the startups focus on non-local markets. One of the key questions on the local market side is about what is purchased by the local economy that is produced non-locally, including basics like food, energy, clothing, consumable personal and household products. These are prime markets for local startups.
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Founded in 2002, the blog here continues to be a space of daily conversation about the science of mind and its implications and applications